| Scientific Name | TSN | Taxon Author | Common Name | Name Source | Usage | Reason (ITIS) | Taxon Rank |
|---|
| Chironectes | 552388 | Illiger, 1811 | water opossum yapok | ITIS | valid | | Genus |
| Cuica | 709331 | Liais, 1872 | | ITIS | invalid | junior synonym of Marmosa | Genus |
| Didelphis | 179920 | Linnaeus, 1758 | large American opossums | ITIS | valid | | Genus |
| Didelphus | 709332 | Lapham, 1853 | | ITIS | invalid | unavailable, literature misspelling of Didelphis | Genus |
| Didelphys | 709333 | Schreber, 1778 | | ITIS | invalid | unjustified emendation of Didelphis | Genus |
| Gracilinanus | 552389 | Gardner and Creighton, 1989 | | ITIS | valid | | Genus |
| Grymaeomys | 709334 | Burmeister, 1854 | | ITIS | invalid | junior synonym of Marmosa | Genus |
| Hyladelphys | 709335 | Voss, Lunde, and Simmons, 2001 | | ITIS | valid | | Genus |
| Lestodelphys | 552390 | Tate, 1934 | Patagonian opposum | ITIS | valid | | Genus |
| Leucodidelphys | 709336 | Krumbiegel, 1941 | | ITIS | invalid | unjustified emendation of Didelphis | Genus |
| Lutreolina | 552391 | Thomas, 1910 | thick-tailed opossum | ITIS | valid | | Genus |
| Marmosa | 552392 | Gray, 1821 | mouse opossums | ITIS | valid | | Genus |
| Marmosops | 552393 | Matschie, 1916 | | ITIS | valid | | Genus |
| Metachirus | 552394 | Burmeister, 1854 | brown four-eyed opossum | ITIS | valid | | Genus |
| Micoureus | 552395 | Lesson, 1842 | | ITIS | valid | | Genus |
| Microdelphys | 709337 | Burmeister, 1856 | | ITIS | invalid | junior synonym of Monodelphis | Genus |
| Microdidelphys | 709338 | Trouessart, 1898 | | ITIS | invalid | unavailable, literature misspelling of Monodelphis | Genus |
| Monodelphis | 552396 | Burnett, 1830 | short-tailed opossums | ITIS | valid | | Genus |
| Philander | 552397 | Brisson, 1762 | black four-eyed opossums gray four-eyed opossums | ITIS | valid | | Genus |
| Thylacotherium | 709340 | Lund, 1839 | | ITIS | invalid | homonym & junior synonym of Didelphis | Genus |
| Thylamys | 609790 | Gray, 1843 | | ITIS | valid | | Genus |
| Tlacuatzin | 709341 | Voss and Jansa, 2003 | | ITIS | valid | | Genus |
